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Biometric Dosing of Hormones

Hormones are truly "bio-identical" only if they are biomimetic, an imitation of those found in the system and are able to imitate the natural way.

New research shines brilliant light on healthy hormone replacement therapy (HRT), indicating that women must cycle their hormones and have a menstrual bleed to be truly safe from cardiovascular events. Based on the latest Danish research, hormonal regimens linked with steady monthly cycle presents a smaller danger of cardiovascular illnesses on women than those constant combination of estrogen/progesterone/progestin therapy because this forbids menstrual flow.

The study also found that overall there was no increased risk of heart attacks in present users of HRT compared to women who had never taken hormones.

The study is a perfect assertion that Cyclical hormone therapy (estrogen, succeeded by a combination of estrogen and progesterone) and biomimetic hormone restoration therapy (BHRT) are in fact less risky than constant combination of substitutes be it bio-identical or artificial.

Follow up:

The primary investigator of this study, *Dr Ellen L_kkegaard, a gynecologist at the Rigshospitalet in Copenhagen, Denmark, stated "The primary message is that when hormone therapy is designated for a woman, then a cyclic combined regimen should be favored, and that application via the skin or the vagina is associated with a decreased risk of myocardial infarction."

About 698,098 healthy Danish women between ages 51-69 became the subject of this study that is believed to be the largest yet in numbers to screen the outcome of HRT since the Women's Health Initiative (WHI) trial in 1991.

More women are considering Hormone Replacement Therapy (HRT) each day, but because of countless products are being offered in the market, they find it confusing on which kind to choose. As a result women are turning to their doctors for assistance.

Uncertainty about HRT started when The National Institute of Health (NIH) patronized the WHI, a research of more than 161,000 women, which was designed to distinguish the advantages and risks of using hormone restoration therapy to avert chronic diseases like heart disease, breast cancer and osteoporosis in postmenopausal women.

The research was concluded mid-stream in 2002 when WHI researchers discovered that the risks of this approach using synthetic therapy surpassed the safety boundaries established at the beginning of the study.

The result of WHI research covered only women over 65 who were on artificial hormone replacement therapy which comprised of drugs such as PremPro and Premarin only.

The WHI showed that the amount of artificial HRT in a fixed, small amount routine was dangerous to women above 65, primarily with strokes and heart attacks. After 14 years and almost $800 million taxpayer dollars, the excessively emphasized negative outcomes of the WHI were released in May 2002.

The media twist caused millions of women to instantly stop taking their Premarin or Prempro, or any other product deemed a hormone by their doctors, thus leaving millions of symptomatic women without any true clinical guidance.

Interestingly, the WHI never looked at hormones, just drugs with "hormone-like" results that were dosed in a regimen far from that of human replacement. The research made us see that conjugated equine estrogens (from pregnant mare urine) and artificial progestin (Prempro) when put in small amounts everyday in fixed quantity proved risky to females with a conflicting information from the same research body a few years back saying that Prempo showed helpful results as well. Premarin, a drug that was also put to test appeared to have less negative effects. Compounded bio-identical hormones in static doses were not included in the study because they are prescribed and dosed too many various ways.

Now, in the wake of the WHI, acquiring hormones is hard. Physicians are doubtful of the "Standard Of Care" approved artificial drugs. Finding established insurance-covered mainstream physicians to prescribe even bio-identical hormones is a difficulty.

HRT Story
Life expectancy of women in developed countries since 1900 have risen from ages 47 to well over age 80. The typical onslaught of menopause has been recorded at 50 years old for the last 150 years. That means most women are living at least thirty years longer than they did at the turn of the century, and about one third of their lives after menopause. It is guessed that 80 percent of women experience an assortment of transiently weakening symptoms in menopause and 30 percent of those are classified as severe.

Ten years before having hot flashes and migraine women are likely to experience negative and erratic changes in their monthly periods. Insomnia, fatigue and nervousness add to the progression of aging. Painful joints and plummeting sex hormones can usually create a life in constant suffering.

Symptoms of menopause can start as early as the late thirties - yet they are the same miserable disabilities that the elderly face. The growth of the aging process starts to quicken when the hormones drop. Aging usually adds pathology in numerous forms such as cancer, diabetes, heart disease, glaucoma, depression, and Alzheimer's. Could it be possible for menopause to signify a sign of a disease attributed to aging since the dropping of hormones tells the body that it is getting old?

Doctors are encouraged to come up with a feasible answer to numerous menopausal problems for Baby Boomers. Almost none, nevertheless, have the correct information on how to prescribe hormones.

Sad to say due to lack of understanding some doctors are recommending the consumption of artificial drugs deemed hormone-like effects. Besides the risk of synthetics, as shown by the WHI outcomes, these hormones are prescribed in static dosing format, which is not natural to the body. Will aggressive diseases linked with aging be relieved by exactly replacing youthful hormone levels that are lost?

Natural Hormone Replacement Therapy - What is it?
Women are starting to see that going without their hormones is unnecessary at best and miserable and dangerous at worst.

What occurs when hormone replacement therapy can actually copy youthful hormones and not just cover some signs? After all, logic dictates that young women aren't susceptible to glaucoma, cancer and heart disease, to list a few. The sole significance among young and older women is the reproductive ability and their assisting hormones. Medicine can testify that many women with normal hormones are not likely to develop such illnesses.

Common sense prescribes that natural hormone replacement (not synthetic drugs with hormone-like outcomes), in and of itself, does not cause cancer. All young women will die if estrogen and progesterone or even testosterone leads to cancer. If reasoning like that informs us that estrogen doesn't really cause cancer in and of itself, then there should be more to the story-such as what kind of estrogen, how much and when to take it.

Many of us believe that if a hormone is natural or developed in a lab then its ingredients are the same to that of the hormones in the body. End of story. What if it's not the last of the story? What if it is important that the body can really identify the substance coming in as a hormone? The same hormone molecules that are considerably developed in a laboratory triggers the action of hormone receptors within the system and can be known as "natural" but differ in composition from naturally occurring hormones but in feasible synergistic system.

Bio-identical Hormone Replacement Therapy (BHRT)
The word bio identical has become noted for something that is false. Scientifically, the term bio-identical means that look-alike molecules synthesized from plants are substituted for our own endogenously-produced hormone molecules. Bio-identical hormone products are created from natural sources of plant hormones which match the chemical framework of hormones developed by the human body. It is the estimation that the system cannot distinguish the bio-identical hormones from ones the women ovaries make.

Many bio-identical HRT products are prepared at compounding pharmacies from plant derived raw materials such as wild yams or soybeans that have an ability to simulate the molecules found in nature.

Biomimetic
Molecules are not the only essential factors. The way of the receptor site in which the hormones are obtained and are forced may pose an important part in HRT efficiency.

The Wiley Protocol, for instance, is based on the premise that hormones can be accurately "bio-identical" only if they are biomimetic - this entails that they should mimic those seen in the body as well as mimic the natural biological process. A woman's body does not produce hormones statically (the same amount each day) but in a rolling and changing rhythm over a 28 day cycle. It signifies that hormones from natural plants can exactly be known as bio-identical when they are given in an alternative way.

What is absent from different bio-identical and artificial hormone replacement therapies is the common wave-like rhythm of the hormone blood levels in a normal menstrual period of a young woman.

A menstrual cycle of a woman traces a natural pace such as that of her body's. Bio-identical and other artificial hormone replacement therapies have not taken into full concern the biological clock that influences the usual tempo taking place every day. This regular rhythm traces one 24 hour spin of the planet. For 28 days the moon tracks the echo of that cycle - and so does the body.

So what is meant by "the rhythm"? Our body traces a regular flow that is dispensed by a main regulator that resembles that of a conductor, working up from one section to another and obtaining its key cues to stay the same 24 hours a day. Our hormones follow the tempo controlling all endocrine functions primarily of a woman's reproductive health.

Bio-identical hormones can precisely be called bio-identical when the hormones being substituted do not just imitate those within the body but also the normal biological procedure. This approach may open the door for a new perception at the possible decline or disappearance of the symptoms and disease conditions associated with menopause and aging.

The Wiley Protocol makes use of the regular pacing in nature to create appropriate amounts of estradiol and natural progesterone that imitates the normal hormones developed by a younger body.

A Clinical Study
Women require hormone restoration that is established to be safe and reliable. An upcoming study about Bio-identical Hormones On Trial, or B.H.O.T., will take place at the College of Nursing and Health Sciences at the University of Texas, Tyler. The main function of the research is to study clinical outcomes and value of life indicators of patients acquiring BHRT at 10 to 12 main health care contributors. This study will be the first of its type to trace and quantify outcomes founded on dosing and models of administration of BHRT.

Biomimetic Hormone Restoration and Healthcare Costs
With the use of authentic biomimetic hormone restoration therapy, women may come across help from menopausal symptoms and thus live a more comfortable and healthy life. Less visits to the doctors would mean less number of medicare and other insurance repayments from the never-ending prescriptions and operations. Most women would then experience a better quality of life and prevent the bitter effects of being without hormones.

Today, reliable doctors are considering the more efficient biomimetic hormone restoration. By the year 2030 about 57.8 million baby boomers ages 66 and 84 will be living with this health conditions. Those who opt to use the Wiley Protocol, could live to have a better life. See the possibility.